IVIG Dose Calculator

About the IVIG Dose Calculator

Intravenous immunoglobulin (IVIG) is a pooled human IgG product used in a range of autoimmune, inflammatory, and immunodeficiency settings. Dosing varies by indication — from replacement dosing for primary immunodeficiency to higher immunomodulatory courses used in conditions such as Kawasaki disease — so the arithmetic depends on the clinical context, product concentration, and total course length.

This IVIG dose calculator provides indication-specific reference values for eight common scenarios, computes the total course dose, converts grams to volume based on product concentration (5% or 10%), and estimates the number of bottles needed. It is designed as a calculation worksheet, not a procedure guide.

The page keeps the math visible for comparison and planning purposes and leaves product selection, rate limits, and local handling instructions to the prescribing source and institution.

When This Page Helps

IVIG calculations depend on the indication, the patient weight, the product concentration, and the chosen reference rate assumption, so manual conversion is easy to get wrong. This calculator keeps the grams, volume, bottle count, and reference time aligned in one place so the arithmetic can be checked consistently.

How to Use the Inputs

1. Enter the patient body weight in kg or lb, or use a weight preset button.
2. Select the clinical indication from the dropdown to load a reference dose.
3. Choose the IVIG product concentration (5% or 10%).
4. Optionally enter a custom dose in g/kg/day to override the reference value.
5. Review the daily dose, total course dose, infusion volume, estimated bottles, and reference time values.
6. Use the tables as arithmetic reference only.

Example Calculation

Tips & Best Practices

• Check that the selected indication matches the worksheet scenario before interpreting the result.
• Compare 5% and 10% values carefully, since the concentration changes the volume math even when grams stay the same.
• Round bottle counts separately from gram dose if you are doing procurement planning.
• Reference rates are assumptions for the worksheet, not product labels.
• Record the assumptions used so the worksheet can be reviewed later.

Reading the Worksheet

This page is built to compare indication-based dose assumptions, not to direct treatment. The same patient weight can produce very different gram and volume totals depending on the selected indication and concentration.

Concentration Math

The concentration setting changes the volume calculation only. A 5% product has half the concentration of a 10% product, so the same gram dose requires twice the volume.

Course Planning

The course total is the per-day amount multiplied by the number of days selected for the worksheet scenario. That makes it easy to compare one course against another without changing the underlying arithmetic.

Frequently Asked Questions

• Why does the worksheet include a reference rate?

  The reference rate is there so the math can show the time implied by a chosen rate assumption. It is not a substitute for local product instructions.

• What is the difference between 5% and 10% IVIG?

  5% IVIG contains 50 mg/mL and 10% IVIG contains 100 mg/mL, so the same gram dose converts to different volumes. The calculator uses that concentration change directly in the volume math.

• Why keep indication-specific rows?

  Different indications use different reference doses and course lengths. The table makes those arithmetic differences visible in one place.

• Can this page replace prescribing information?

  No. It is a calculation worksheet that shows how the numbers relate to each other. Product labeling and local procedures still govern actual use.