Calculate intravenous immunoglobulin (IVIG) dose by weight and indication including ITP, Kawasaki, Guillain-Barré, CIDP, and immunodeficiency as a reference worksheet.
Intravenous immunoglobulin (IVIG) is a pooled human IgG product used in a range of autoimmune, inflammatory, and immunodeficiency settings. Dosing varies by indication — from replacement dosing for primary immunodeficiency to higher immunomodulatory courses used in conditions such as Kawasaki disease — so the arithmetic depends on the clinical context, product concentration, and total course length.
This IVIG dose calculator provides indication-specific reference values for eight common scenarios, computes the total course dose, converts grams to volume based on product concentration (5% or 10%), and estimates the number of bottles needed. It is designed as a calculation worksheet, not a procedure guide.
The page keeps the math visible for comparison and planning purposes and leaves product selection, rate limits, and local handling instructions to the prescribing source and institution.
IVIG calculations depend on the indication, the patient weight, the product concentration, and the chosen reference rate assumption, so manual conversion is easy to get wrong. This calculator keeps the grams, volume, bottle count, and reference time aligned in one place so the arithmetic can be checked consistently.
Total daily dose (g) = weight (kg) × dose (g/kg/day). Total course dose = daily dose × number of days. Volume (mL) = total dose (g) ÷ concentration (g/mL). Reference time ≈ volume (mL) ÷ (reference rate mL/kg/hr × weight kg). Concentration: 5% = 0.05 g/mL = 50 mg/mL; 10% = 0.10 g/mL = 100 mg/mL.
Result: 28 g/day × 5 days = 140 g total course (2,800 mL at 5%). Reference time ~10 hrs/day.
A 70 kg GBS example: 0.4 g/kg/day × 70 kg = 28 g/day. Over 5 days: 140 g total. At 5% (50 mg/mL): 28 g ÷ 0.05 = 560 mL/day. At a 4 mL/kg/hr reference rate, the worksheet shows the time implied by that rate.
This page is built to compare indication-based dose assumptions, not to direct treatment. The same patient weight can produce very different gram and volume totals depending on the selected indication and concentration.
The concentration setting changes the volume calculation only. A 5% product has half the concentration of a 10% product, so the same gram dose requires twice the volume.
The course total is the per-day amount multiplied by the number of days selected for the worksheet scenario. That makes it easy to compare one course against another without changing the underlying arithmetic.
Last updated:
This worksheet converts common IVIG course ranges into total grams, volume, and infusion-time context using indication-specific planning assumptions.
The reference rate is there so the math can show the time implied by a chosen rate assumption. It is not a substitute for local product instructions.
5% IVIG contains 50 mg/mL and 10% IVIG contains 100 mg/mL, so the same gram dose converts to different volumes. The calculator uses that concentration change directly in the volume math.
Different indications use different reference doses and course lengths. The table makes those arithmetic differences visible in one place.
No. It is a calculation worksheet that shows how the numbers relate to each other. Product labeling and local procedures still govern actual use.